PHIP drives glioblastoma motility and invasion by regulating the focal adhesion complex

The invasive behavior of glioblastoma is essential to its aggressive potential. Here, we show that pleckstrin homology domain interacting protein (PHIP), acting through effects on the force transduction layer of the focal adhesion complex, drives glioblastoma motility and invasion. Immunofluorescenc...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: de Semir, David, Bezrookove, Vladimir, Nosrati, Mehdi, Scanlon, Kara R., Singer, Eric, Judkins, Jonathon, Rieken, Christopher, Wu, Clayton, Shen, Julia, Schmudermayer, Christina, Dar, Altaf A., Miller, James R., Cobbs, Charles, Yount, Garret, Desprez, Pierre-Yves, Debs, Robert J., Salomonis, Nathan, McAllister, Sean, Cleaver, James E., Soroceanu, Liliana, Kashani-Sabet, Mohammed
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183218/
https://ncbi.nlm.nih.gov/pubmed/32273388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914505117
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