Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase

Macrophages are a key component of the innate immune system. In this study, we investigate how focal adhesion kinase (FAK) and the related kinase Pyk2 integrate adhesion signaling and growth factor receptor signaling to regulate diverse macrophage functions. Primary bone marrow macrophages isolated...

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Detalhes bibliográficos
Main Authors: Owen, Katherine A., Pixley, Fiona J., Thomas, Keena S., Vicente-Manzanares, Miguel, Ray, Brianne J., Horwitz, Alan F., Parsons, J. Thomas, Beggs, Hilary E., Stanley, E. Richard, Bouton, Amy H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140030/
https://ncbi.nlm.nih.gov/pubmed/18070912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708093
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