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The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility.
The Src family of protein tyrosine kinases is involved in transducing signals at sites of cellular adhesion. In particular, the v-Src oncoprotein resides in cellular focal adhesions, where it induces tyrosine phosphorylation of pp125FAK and focal adhesion loss during transformation. v-Src is translo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1998
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170360/ https://ncbi.nlm.nih.gov/pubmed/9427743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.1.81 |
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