Induced expression of microsomal cytochrome b(5) determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)

ABSTRACT: The microsomal protein cytochrome b (5), which is located in the membrane of the endoplasmic reticulum, has been shown to modulate many reactions catalyzed by cytochrome P450 (CYP) enzymes. We investigated the influence of exposure to the anticancer drug ellipticine and to two environmenta...

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Detalhes bibliográficos
Publicado no:Monatsh Chem
Main Authors: Stiborová, Marie, Moserová, Michaela, Mrízová, Iveta, Dračínská, Helena, Martínek, Václav, Indra, Radek, Frei, Eva, Adam, Vojtěch, Kizek, René, Schmeiser, Heinz H., Kubáčková, Kateřina, Arlt, Volker M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2016
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828491/
https://ncbi.nlm.nih.gov/pubmed/27110040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-015-1636-z
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