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Induced expression of microsomal cytochrome b(5) determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)

ABSTRACT: The microsomal protein cytochrome b (5), which is located in the membrane of the endoplasmic reticulum, has been shown to modulate many reactions catalyzed by cytochrome P450 (CYP) enzymes. We investigated the influence of exposure to the anticancer drug ellipticine and to two environmenta...

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Bibliografiska uppgifter
I publikationen:Monatsh Chem
Huvudupphovsmän: Stiborová, Marie, Moserová, Michaela, Mrízová, Iveta, Dračínská, Helena, Martínek, Václav, Indra, Radek, Frei, Eva, Adam, Vojtěch, Kizek, René, Schmeiser, Heinz H., Kubáčková, Kateřina, Arlt, Volker M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Vienna 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828491/
https://ncbi.nlm.nih.gov/pubmed/27110040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-015-1636-z
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