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Induced expression of microsomal cytochrome b(5) determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)

ABSTRACT: The microsomal protein cytochrome b (5), which is located in the membrane of the endoplasmic reticulum, has been shown to modulate many reactions catalyzed by cytochrome P450 (CYP) enzymes. We investigated the influence of exposure to the anticancer drug ellipticine and to two environmenta...

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Dades bibliogràfiques
Publicat a:Monatsh Chem
Autors principals: Stiborová, Marie, Moserová, Michaela, Mrízová, Iveta, Dračínská, Helena, Martínek, Václav, Indra, Radek, Frei, Eva, Adam, Vojtěch, Kizek, René, Schmeiser, Heinz H., Kubáčková, Kateřina, Arlt, Volker M.
Format: Artigo
Idioma:Inglês
Publicat: Springer Vienna 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828491/
https://ncbi.nlm.nih.gov/pubmed/27110040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-015-1636-z
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