Induced expression of microsomal cytochrome b(5) determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)

ABSTRACT: The microsomal protein cytochrome b (5), which is located in the membrane of the endoplasmic reticulum, has been shown to modulate many reactions catalyzed by cytochrome P450 (CYP) enzymes. We investigated the influence of exposure to the anticancer drug ellipticine and to two environmenta...

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Publicado en:Monatsh Chem
Autores principales: Stiborová, Marie, Moserová, Michaela, Mrízová, Iveta, Dračínská, Helena, Martínek, Václav, Indra, Radek, Frei, Eva, Adam, Vojtěch, Kizek, René, Schmeiser, Heinz H., Kubáčková, Kateřina, Arlt, Volker M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Vienna 2016
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Original Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828491/
https://ncbi.nlm.nih.gov/pubmed/27110040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-015-1636-z
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