Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation

The Warburg effect is probably the most prominent metabolic feature of cancer cells, although little is known about the underlying mechanisms and consequences. Here, we set out to study these features in detail in a number of leukemia backgrounds. The transcriptomes of human CB CD34(+) cells transdu...

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Publicat a:PLoS One
Autors principals: Sontakke, Pallavi, Koczula, Katarzyna M., Jaques, Jennifer, Wierenga, Albertus T. J., Brouwers-Vos, Annet Z., Pruis, Maurien, Günther, Ulrich L., Vellenga, Edo, Schuringa, Jan Jacob
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824381/
https://ncbi.nlm.nih.gov/pubmed/27055152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153226
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