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Modeling of Chronic Myeloid Leukemia: An Overview of In Vivo Murine and Human Xenograft Models

Over the past years, a wide variety of in vivo mouse models have been generated in order to unravel the molecular pathology of Chronic Myeloid Leukemia (CML) and to develop and improve therapeutic approaches. These models range from (conditional) transgenic models, knock-in models, and murine bone m...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Sontakke, Pallavi, Jaques, Jenny, Vellenga, Edo, Schuringa, Jan Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014953/
https://ncbi.nlm.nih.gov/pubmed/27642303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1625015
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