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Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation

The Warburg effect is probably the most prominent metabolic feature of cancer cells, although little is known about the underlying mechanisms and consequences. Here, we set out to study these features in detail in a number of leukemia backgrounds. The transcriptomes of human CB CD34(+) cells transdu...

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Vydáno v:PLoS One
Hlavní autoři: Sontakke, Pallavi, Koczula, Katarzyna M., Jaques, Jennifer, Wierenga, Albertus T. J., Brouwers-Vos, Annet Z., Pruis, Maurien, Günther, Ulrich L., Vellenga, Edo, Schuringa, Jan Jacob
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824381/
https://ncbi.nlm.nih.gov/pubmed/27055152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153226
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