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Convergence of Hypoxia and TGFβ Pathways on Cell Cycle Regulation in Human Hematopoietic Stem/Progenitor Cells

Although it has been shown that HIF1 and 2 fulfill essential roles within the hematopoietic system and in the regulation of HSC fate, little is currently known about the specific mechanisms that are involved. We identified transcriptome changes induced by hypoxia, constitutively active HIF1((P402/56...

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Detalhes bibliográficos
Main Authors: Wierenga, Albertus T. J., Vellenga, Edo, Schuringa, Jan Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970968/
https://ncbi.nlm.nih.gov/pubmed/24686421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093494
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