Convergence of Hypoxia and TGFβ Pathways on Cell Cycle Regulation in Human Hematopoietic Stem/Progenitor Cells

Although it has been shown that HIF1 and 2 fulfill essential roles within the hematopoietic system and in the regulation of HSC fate, little is currently known about the specific mechanisms that are involved. We identified transcriptome changes induced by hypoxia, constitutively active HIF1((P402/56...

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Bibliographic Details
Main Authors: Wierenga, Albertus T. J., Vellenga, Edo, Schuringa, Jan Jacob
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970968/
https://ncbi.nlm.nih.gov/pubmed/24686421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093494
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