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Maximal STAT5-Induced Proliferation and Self-Renewal at Intermediate STAT5 Activity Levels
The level of transcription factor activity critically regulates cell fate decisions, such as hematopoietic stem cell (HSC) self-renewal and differentiation. We introduced STAT5A transcriptional activity into human HSCs/progenitor cells in a dose-dependent manner by overexpression of a tamoxifen-indu...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2573230/ https://ncbi.nlm.nih.gov/pubmed/18779318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01025-08 |
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