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Constitutive Activation of STAT5A Promotes Human Hematopoietic Stem Cell Self-Renewal and Erythroid Differentiation

Activation of the transcription factor signal transducer and activator of transcription (STAT)5 is involved in various aspects of hematopoiesis, affecting cell proliferation, differentiation, and cell survival. Constitutive activation of STAT5 has also been associated with leukemic transformation. W...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schuringa, Jan Jacob, Chung, Ki Young, Morrone, Giovanni, Moore, Malcolm A.S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212750/
https://ncbi.nlm.nih.gov/pubmed/15353555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041024
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