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ELMO1 Is Upregulated in AML CD34+ Stem/Progenitor Cells, Mediates Chemotaxis and Predicts Poor Prognosis in Normal Karyotype AML

Both normal as well leukemic hematopoietic stem cells critically depend on their microenvironment in the bone marrow for processes such as self-renewal, survival and differentiation, although the exact pathways that are involved remain poorly understood. We performed transcriptome analysis on primit...

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Detalhes bibliográficos
Main Authors: Capala, Marta E., Vellenga, Edo, Schuringa, Jan Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216115/
https://ncbi.nlm.nih.gov/pubmed/25360637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111568
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