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Is it important to decipher the heterogeneity of “normal karyotype AML”?

Almost half of adult acute myelogenous leukemia (AML) is normal cytogenetically, and this subgroup shows a remarkable heterogeneity of genetic mutations at the molecular level and an intermediate response to therapy. The finding of recurrent cytogenetic abnormalities has influenced, in a primary way...

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Detalhes bibliográficos
Autor principal: Nimer, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654590/
https://ncbi.nlm.nih.gov/pubmed/18342811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beha.2007.11.010
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