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Mitochondrial polymerase gamma dysfunction and aging cause cardiac nuclear DNA methylation changes

Cardiomyopathy (CM) is an intrinsic weakening of myocardium with contractile dysfunction and congestive heart failure (CHF). CHF has been postulated to result from decreased mitochondrial energy production and oxidative stress. Effects of decreased mitochondrial oxygen consumption also can accelerat...

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Bibliografische gegevens
Gepubliceerd in:Physiol Genomics
Hoofdauteurs: Koczor, Christopher A., Ludlow, Ivan, Fields, Earl, Jiao, Zhe, Ludaway, Tomika, Russ, Rodney, Lewis, William
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824151/
https://ncbi.nlm.nih.gov/pubmed/26757797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00099.2015
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