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Mitochondrial polymerase gamma dysfunction and aging cause cardiac nuclear DNA methylation changes
Cardiomyopathy (CM) is an intrinsic weakening of myocardium with contractile dysfunction and congestive heart failure (CHF). CHF has been postulated to result from decreased mitochondrial energy production and oxidative stress. Effects of decreased mitochondrial oxygen consumption also can accelerat...
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出版年: | Physiol Genomics |
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主要な著者: | , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
American Physiological Society
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824151/ https://ncbi.nlm.nih.gov/pubmed/26757797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00099.2015 |
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