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Mitochondrial polymerase gamma dysfunction and aging cause cardiac nuclear DNA methylation changes

Cardiomyopathy (CM) is an intrinsic weakening of myocardium with contractile dysfunction and congestive heart failure (CHF). CHF has been postulated to result from decreased mitochondrial energy production and oxidative stress. Effects of decreased mitochondrial oxygen consumption also can accelerat...

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Foilsithe in:Physiol Genomics
Main Authors: Koczor, Christopher A., Ludlow, Ivan, Fields, Earl, Jiao, Zhe, Ludaway, Tomika, Russ, Rodney, Lewis, William
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824151/
https://ncbi.nlm.nih.gov/pubmed/26757797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00099.2015
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