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Mitochondrial polymerase gamma dysfunction and aging cause cardiac nuclear DNA methylation changes

Cardiomyopathy (CM) is an intrinsic weakening of myocardium with contractile dysfunction and congestive heart failure (CHF). CHF has been postulated to result from decreased mitochondrial energy production and oxidative stress. Effects of decreased mitochondrial oxygen consumption also can accelerat...

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Détails bibliographiques
Publié dans:Physiol Genomics
Auteurs principaux: Koczor, Christopher A., Ludlow, Ivan, Fields, Earl, Jiao, Zhe, Ludaway, Tomika, Russ, Rodney, Lewis, William
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824151/
https://ncbi.nlm.nih.gov/pubmed/26757797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00099.2015
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