GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate

The gradual reprogramming of haematopoietic precursors into the T-cell fate is characterized by at least two sequential developmental stages. Following Notch1-dependent T-cell lineage specification during which the first T-cell lineage genes are expressed and myeloid and dendritic cell potential is...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Van de Walle, Inge, Dolens, Anne-Catherine, Durinck, Kaat, De Mulder, Katrien, Van Loocke, Wouter, Damle, Sagar, Waegemans, Els, De Medts, Jelle, Velghe, Imke, De Smedt, Magda, Vandekerckhove, Bart, Kerre, Tessa, Plum, Jean, Leclercq, Georges, Rothenberg, Ellen V., Van Vlierberghe, Pieter, Speleman, Frank, Taghon, Tom
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823830/
https://ncbi.nlm.nih.gov/pubmed/27048872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11171
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