PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation

Transcriptional control of hematopoiesis involves complex regulatory networks and functional perturbations in one of these components often results in malignancies. Loss-of-function mutations in PHF6, encoding a presumed epigenetic regulator, have been primarily described in T cell acute lymphoblast...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Loontiens, Siebe, Dolens, Anne-Catherine, Strubbe, Steven, Van de Walle, Inge, Moore, Finola E., Depestel, Lisa, Vanhauwaert, Suzanne, Matthijssens, Filip, Langenau, David M., Speleman, Frank, Van Vlierberghe, Pieter, Durinck, Kaat, Taghon, Tom
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672048/
https://ncbi.nlm.nih.gov/pubmed/33251223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.599472
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