T-lymphoid differentiation potential measured in vitro is higher in CD34(+)CD38(−/lo) hematopoietic stem cells from umbilical cord blood than from bone marrow and is an intrinsic property of the cells

BACKGROUND: Human bone marrow and umbilical cord blood are sources of allogeneic hematopoietic stem cells for transplantation, which is a life-saving treatment in a variety of diseases but is burdened by delayed T-cell reconstitution. Observational studies evaluating T-cell reconstitution in post-tr...

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Autors principals: De Smedt, Magda, Leclercq, Georges, Vandekerckhove, Bart, Kerre, Tessa, Taghon, Tom, Plum, Jean
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2011
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084910/
https://ncbi.nlm.nih.gov/pubmed/21330325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.036343
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