Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells

Melatonin, a molecule produced throughout the animal and plant kingdoms, and berberine, a plant derived agent, both exhibit antitumor and multiple biological and pharmacological effects, but they have never been combined altogether for the inhibition of human lung cancers. In this study, we investig...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Lu, Jian-Jun, Fu, Lingyi, Tang, Zhipeng, Zhang, Changlin, Qin, Lijun, Wang, Jingshu, Yu, Zhenlong, Shi, Dingbo, Xiao, Xiangsheng, Xie, Fangyun, Huang, Wenlin, Deng, Wuguo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823085/
https://ncbi.nlm.nih.gov/pubmed/26672764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6407
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