Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells

Melatonin, a molecule produced throughout the animal and plant kingdoms, and berberine, a plant derived agent, both exhibit antitumor and multiple biological and pharmacological effects, but they have never been combined altogether for the inhibition of human lung cancers. In this study, we investig...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Lu, Jian-Jun, Fu, Lingyi, Tang, Zhipeng, Zhang, Changlin, Qin, Lijun, Wang, Jingshu, Yu, Zhenlong, Shi, Dingbo, Xiao, Xiangsheng, Xie, Fangyun, Huang, Wenlin, Deng, Wuguo
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823085/
https://ncbi.nlm.nih.gov/pubmed/26672764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6407
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