KLF4 downregulates hTERT expression and telomerase activity to inhibit lung carcinoma growth

Krüppel-like factor 4 (KLF4) is a transcription factor that contributes to diverse cellular processes and serves as a tumor suppressor or oncogene in various cancers. Previously, we have reported on the tumor suppressive function of KLF4 in lung cancer; however, its precise regulatory mechanism rema...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Hu, Wenxian, Jia, Yunlu, Xiao, Xiangsheng, Lv, Kezhen, Chen, Yongxia, Wang, Linbo, Luo, Xiao, Liu, Tianze, Li, Wenbin, Li, Yixin, Zhang, Changlin, Yu, Zhenglong, Huang, Wenlin, Sun, Bing, Deng, Wu-guo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288155/
https://ncbi.nlm.nih.gov/pubmed/27153563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9141
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