KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway

Melanoma is an aggressive cutaneous malignancy, illuminating the exact mechanisms and finding novel therapeutic targets are urgently needed. In this study, we identified KMT2A as a potential target, which promoted the growth of human melanoma cells. KMT2A knockdown significantly inhibited cell viabi...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Zhang, Changlin, Song, Chen, Liu, Tianze, Tang, Ranran, Chen, Miao, Gao, Fan, Xiao, Binyi, Qin, Ge, Shi, Fen, Li, Wenbin, Li, Yixin, Fu, Xiaoyan, Shi, Dingbo, Xiao, Xiangsheng, Kang, Lan, Huang, Wenlin, Wu, Xiaojun, Tang, Bing, Deng, Wuguo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550845/
https://ncbi.nlm.nih.gov/pubmed/28726783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.285
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