KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway

Melanoma is an aggressive cutaneous malignancy, illuminating the exact mechanisms and finding novel therapeutic targets are urgently needed. In this study, we identified KMT2A as a potential target, which promoted the growth of human melanoma cells. KMT2A knockdown significantly inhibited cell viabi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Zhang, Changlin, Song, Chen, Liu, Tianze, Tang, Ranran, Chen, Miao, Gao, Fan, Xiao, Binyi, Qin, Ge, Shi, Fen, Li, Wenbin, Li, Yixin, Fu, Xiaoyan, Shi, Dingbo, Xiao, Xiangsheng, Kang, Lan, Huang, Wenlin, Wu, Xiaojun, Tang, Bing, Deng, Wuguo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550845/
https://ncbi.nlm.nih.gov/pubmed/28726783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.285
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