KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway

Melanoma is an aggressive cutaneous malignancy, illuminating the exact mechanisms and finding novel therapeutic targets are urgently needed. In this study, we identified KMT2A as a potential target, which promoted the growth of human melanoma cells. KMT2A knockdown significantly inhibited cell viabi...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Zhang, Changlin, Song, Chen, Liu, Tianze, Tang, Ranran, Chen, Miao, Gao, Fan, Xiao, Binyi, Qin, Ge, Shi, Fen, Li, Wenbin, Li, Yixin, Fu, Xiaoyan, Shi, Dingbo, Xiao, Xiangsheng, Kang, Lan, Huang, Wenlin, Wu, Xiaojun, Tang, Bing, Deng, Wuguo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550845/
https://ncbi.nlm.nih.gov/pubmed/28726783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.285
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