KMT2A promotes melanoma cell growth by targeting hTERT signaling pathway

Melanoma is an aggressive cutaneous malignancy, illuminating the exact mechanisms and finding novel therapeutic targets are urgently needed. In this study, we identified KMT2A as a potential target, which promoted the growth of human melanoma cells. KMT2A knockdown significantly inhibited cell viabi...

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Bibliografiska uppgifter
I publikationen:Cell Death Dis
Huvudupphovsmän: Zhang, Changlin, Song, Chen, Liu, Tianze, Tang, Ranran, Chen, Miao, Gao, Fan, Xiao, Binyi, Qin, Ge, Shi, Fen, Li, Wenbin, Li, Yixin, Fu, Xiaoyan, Shi, Dingbo, Xiao, Xiangsheng, Kang, Lan, Huang, Wenlin, Wu, Xiaojun, Tang, Bing, Deng, Wuguo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550845/
https://ncbi.nlm.nih.gov/pubmed/28726783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.285
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