RFPL3 and CBP synergistically upregulate hTERT activity and promote lung cancer growth

hTERT is the key component of telomerase and its overactivation contributes to maintaining telomere length and cell immortalization. Previously, we identified RFPL3 as a new transcription activator of hTERT in lung cancers. However, the exact mechanism of RFPL3 in mediating hTERT activation and its...

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Publicado en:Oncotarget
Autores principales: Qin, Yu, Chen, Wangbing, Xiao, Yao, Yu, Wendan, Cai, Xin, Dai, Meng, Xu, Tingting, Huang, Wenlin, Guo, Wei, Deng, Wuguo, Wu, Taihua
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694978/
https://ncbi.nlm.nih.gov/pubmed/26318425
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