mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation

Precise coordination of cell growth, proliferation and differentiation is essential for the development of multicellular organisms. Here, we report that although the mechanistic target of rapamycin complex 1 (mTORC1) activity is required for chondrocyte growth and proliferation, its inactivation is...

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發表在:Nat Commun
Main Authors: Yan, Bo, Zhang, Zhongmin, Jin, Dadi, Cai, Chen, Jia, Chunhong, Liu, Wen, Wang, Ting, Li, Shengfa, Zhang, Haiyan, Huang, Bin, Lai, Pinglin, Wang, Hua, Liu, Anling, Zeng, Chun, Cai, Daozhang, Jiang, Yu, Bai, Xiaochun
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822018/
https://ncbi.nlm.nih.gov/pubmed/27039827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11151
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