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mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation

Precise coordination of cell growth, proliferation and differentiation is essential for the development of multicellular organisms. Here, we report that although the mechanistic target of rapamycin complex 1 (mTORC1) activity is required for chondrocyte growth and proliferation, its inactivation is...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nat Commun
Main Authors: Yan, Bo, Zhang, Zhongmin, Jin, Dadi, Cai, Chen, Jia, Chunhong, Liu, Wen, Wang, Ting, Li, Shengfa, Zhang, Haiyan, Huang, Bin, Lai, Pinglin, Wang, Hua, Liu, Anling, Zeng, Chun, Cai, Daozhang, Jiang, Yu, Bai, Xiaochun
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822018/
https://ncbi.nlm.nih.gov/pubmed/27039827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11151
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