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mTORC1 Prevents Preosteoblast Differentiation through the Notch Signaling Pathway

The mechanistic target of rapamycin (mTOR) integrates both intracellular and extracellular signals to regulate cell growth and metabolism. However, the role of mTOR signaling in osteoblast differentiation and bone formation is undefined, and the underlying mechanisms have not been elucidated. Here,...

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Dades bibliogràfiques
Publicat a:PLoS Genet
Autors principals: Huang, Bin, Wang, Yongkui, Wang, Wenhao, Chen, Juan, Lai, Pinglin, Liu, Zhongyu, Yan, Bo, Xu, Song, Zhang, Zhongmin, Zeng, Chun, Rong, Limin, Liu, Bin, Cai, Daozhang, Jin, Dadi, Bai, Xiaochun
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524707/
https://ncbi.nlm.nih.gov/pubmed/26241748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005426
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