mTORC1 Prevents Preosteoblast Differentiation through the Notch Signaling Pathway

The mechanistic target of rapamycin (mTOR) integrates both intracellular and extracellular signals to regulate cell growth and metabolism. However, the role of mTOR signaling in osteoblast differentiation and bone formation is undefined, and the underlying mechanisms have not been elucidated. Here,...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Huang, Bin, Wang, Yongkui, Wang, Wenhao, Chen, Juan, Lai, Pinglin, Liu, Zhongyu, Yan, Bo, Xu, Song, Zhang, Zhongmin, Zeng, Chun, Rong, Limin, Liu, Bin, Cai, Daozhang, Jin, Dadi, Bai, Xiaochun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524707/
https://ncbi.nlm.nih.gov/pubmed/26241748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005426
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