mTORC1 Prevents Preosteoblast Differentiation through the Notch Signaling Pathway

The mechanistic target of rapamycin (mTOR) integrates both intracellular and extracellular signals to regulate cell growth and metabolism. However, the role of mTOR signaling in osteoblast differentiation and bone formation is undefined, and the underlying mechanisms have not been elucidated. Here,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Genet
Prif Awduron: Huang, Bin, Wang, Yongkui, Wang, Wenhao, Chen, Juan, Lai, Pinglin, Liu, Zhongyu, Yan, Bo, Xu, Song, Zhang, Zhongmin, Zeng, Chun, Rong, Limin, Liu, Bin, Cai, Daozhang, Jin, Dadi, Bai, Xiaochun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524707/
https://ncbi.nlm.nih.gov/pubmed/26241748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005426
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