Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels

The transcription factor far upstream element binding protein (FBP) binds and activates the MYC promoter when far upstream element is via TFIIH helicase activity early in the transcription cycle. The fundamental biology and pathology of FBP are complex. In some tumors FBP seems pro-oncogenic, wherea...

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Bibliografische gegevens
Gepubliceerd in:Am J Pathol
Hoofdauteurs: Zhou, Weixin, Chung, Yang Jo, Parrilla Castellar, Edgardo R., Zheng, Ying, Chung, Hye-Jung, Bandle, Russell, Liu, Juhong, Tessarollo, Lino, Batchelor, Eric, Aplan, Peter D., Levens, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2016
Onderwerpen:
Regular Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816710/
https://ncbi.nlm.nih.gov/pubmed/26774856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.10.028
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