Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels

The transcription factor far upstream element binding protein (FBP) binds and activates the MYC promoter when far upstream element is via TFIIH helicase activity early in the transcription cycle. The fundamental biology and pathology of FBP are complex. In some tumors FBP seems pro-oncogenic, wherea...

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Bibliografiska uppgifter
I publikationen:Am J Pathol
Huvudupphovsmän: Zhou, Weixin, Chung, Yang Jo, Parrilla Castellar, Edgardo R., Zheng, Ying, Chung, Hye-Jung, Bandle, Russell, Liu, Juhong, Tessarollo, Lino, Batchelor, Eric, Aplan, Peter D., Levens, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2016
Ämnen:
Regular Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816710/
https://ncbi.nlm.nih.gov/pubmed/26774856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.10.028
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