Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels

The transcription factor far upstream element binding protein (FBP) binds and activates the MYC promoter when far upstream element is via TFIIH helicase activity early in the transcription cycle. The fundamental biology and pathology of FBP are complex. In some tumors FBP seems pro-oncogenic, wherea...

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Enregistré dans:
Détails bibliographiques
Publié dans:Am J Pathol
Auteurs principaux: Zhou, Weixin, Chung, Yang Jo, Parrilla Castellar, Edgardo R., Zheng, Ying, Chung, Hye-Jung, Bandle, Russell, Liu, Juhong, Tessarollo, Lino, Batchelor, Eric, Aplan, Peter D., Levens, David
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2016
Sujets:
Regular Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816710/
https://ncbi.nlm.nih.gov/pubmed/26774856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.10.028
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