Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels

The transcription factor far upstream element binding protein (FBP) binds and activates the MYC promoter when far upstream element is via TFIIH helicase activity early in the transcription cycle. The fundamental biology and pathology of FBP are complex. In some tumors FBP seems pro-oncogenic, wherea...

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Dades bibliogràfiques
Publicat a:Am J Pathol
Autors principals: Zhou, Weixin, Chung, Yang Jo, Parrilla Castellar, Edgardo R., Zheng, Ying, Chung, Hye-Jung, Bandle, Russell, Liu, Juhong, Tessarollo, Lino, Batchelor, Eric, Aplan, Peter D., Levens, David
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2016
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816710/
https://ncbi.nlm.nih.gov/pubmed/26774856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.10.028
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