An immediate transcriptional signature associated with response to the histone deacetylase inhibitor Givinostat in T acute lymphoblastic leukemia xenografts

Despite some success with certain hematological malignancies and in contrast with the strong pro-apoptotic effects measured in vitro, the overall response rate of acute lymphoblastic leukemia (ALL) to histone deacetylase inhibitors (HDACis) is low. With the aim to improve the understanding of how HD...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Pinazza, M, Borga, C, Agnusdei, V, Minuzzo, S, Fossati, G, Paganin, M, Michielotto, B, De Paoli, A, Basso, G, Amadori, A, te Kronnie, G, Indraccolo, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816177/
https://ncbi.nlm.nih.gov/pubmed/26764573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.394
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