An immediate transcriptional signature associated with response to the histone deacetylase inhibitor Givinostat in T acute lymphoblastic leukemia xenografts

Despite some success with certain hematological malignancies and in contrast with the strong pro-apoptotic effects measured in vitro, the overall response rate of acute lymphoblastic leukemia (ALL) to histone deacetylase inhibitors (HDACis) is low. With the aim to improve the understanding of how HD...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Dis
Egile Nagusiak: Pinazza, M, Borga, C, Agnusdei, V, Minuzzo, S, Fossati, G, Paganin, M, Michielotto, B, De Paoli, A, Basso, G, Amadori, A, te Kronnie, G, Indraccolo, S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816177/
https://ncbi.nlm.nih.gov/pubmed/26764573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.394
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