An immediate transcriptional signature associated with response to the histone deacetylase inhibitor Givinostat in T acute lymphoblastic leukemia xenografts

Despite some success with certain hematological malignancies and in contrast with the strong pro-apoptotic effects measured in vitro, the overall response rate of acute lymphoblastic leukemia (ALL) to histone deacetylase inhibitors (HDACis) is low. With the aim to improve the understanding of how HD...

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Vydáno v:Cell Death Dis
Hlavní autoři: Pinazza, M, Borga, C, Agnusdei, V, Minuzzo, S, Fossati, G, Paganin, M, Michielotto, B, De Paoli, A, Basso, G, Amadori, A, te Kronnie, G, Indraccolo, S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816177/
https://ncbi.nlm.nih.gov/pubmed/26764573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.394
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