An immediate transcriptional signature associated with response to the histone deacetylase inhibitor Givinostat in T acute lymphoblastic leukemia xenografts

Despite some success with certain hematological malignancies and in contrast with the strong pro-apoptotic effects measured in vitro, the overall response rate of acute lymphoblastic leukemia (ALL) to histone deacetylase inhibitors (HDACis) is low. With the aim to improve the understanding of how HD...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Pinazza, M, Borga, C, Agnusdei, V, Minuzzo, S, Fossati, G, Paganin, M, Michielotto, B, De Paoli, A, Basso, G, Amadori, A, te Kronnie, G, Indraccolo, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816177/
https://ncbi.nlm.nih.gov/pubmed/26764573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.394
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