Loss of Runx2 sensitises osteosarcoma to chemotherapy-induced apoptosis

BACKGROUND: Osteosarcoma (OS) is the most common bone malignancy in the paediatric population, principally affecting adolescents and young adults. Minimal advancements in patient prognosis have been made over the past two decades because of the poor understanding of disease biology. Runx2, a critica...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Br J Cancer
Päätekijät: Roos, Alison, Satterfield, Laura, Zhao, Shuying, Fuja, Daniel, Shuck, Ryan, Hicks, M John, Donehower, Lawrence A, Yustein, Jason T
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Translational Therapeutics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815801/
https://ncbi.nlm.nih.gov/pubmed/26528706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.305
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