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Transglutaminase-2 promotes metastatic and stem-like phenotypes in osteosarcoma

Osteosarcoma (OS) is a highly aggressive mesenchymal malignancy and the most common primary bone tumor in the pediatric population. OS frequently presents with or develops distal metastases. Patients with metastatic disease have extremely poor survival rates, thus necessitating improved molecular in...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Fuja, Daniel G, Rainusso, Nino C, Shuck, Ryan L, Kurenbekova, Lyazat, Donehower, Lawrence A, Yustein, Jason T
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176192/
https://ncbi.nlm.nih.gov/pubmed/30323968
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