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Transglutaminase-2 promotes metastatic and stem-like phenotypes in osteosarcoma

Osteosarcoma (OS) is a highly aggressive mesenchymal malignancy and the most common primary bone tumor in the pediatric population. OS frequently presents with or develops distal metastases. Patients with metastatic disease have extremely poor survival rates, thus necessitating improved molecular in...

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Détails bibliographiques
Publié dans:Am J Cancer Res
Auteurs principaux: Fuja, Daniel G, Rainusso, Nino C, Shuck, Ryan L, Kurenbekova, Lyazat, Donehower, Lawrence A, Yustein, Jason T
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176192/
https://ncbi.nlm.nih.gov/pubmed/30323968
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