Repression of the autophagic response sensitises lung cancer cells to radiation and chemotherapy

BACKGROUND: The cellular autophagic response to radiation is complex. Various cells and tissues respond differentially to radiation, depending on both the dose of exposure and the time post irradiation. In the current study, we determined the autophagosomal and lysosomal response to radiation in lun...

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Bibliographische Detailangaben
Veröffentlicht in:Br J Cancer
Hauptverfasser: Karagounis, Ilias V, Kalamida, Dimitra, Mitrakas, Achilleas, Pouliliou, Stamatia, Liousia, Maria V, Giatromanolaki, Alexandra, Koukourakis, Michael I
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Translational Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973160/
https://ncbi.nlm.nih.gov/pubmed/27380135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.202
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