Repression of the autophagic response sensitises lung cancer cells to radiation and chemotherapy

BACKGROUND: The cellular autophagic response to radiation is complex. Various cells and tissues respond differentially to radiation, depending on both the dose of exposure and the time post irradiation. In the current study, we determined the autophagosomal and lysosomal response to radiation in lun...

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Udgivet i:Br J Cancer
Main Authors: Karagounis, Ilias V, Kalamida, Dimitra, Mitrakas, Achilleas, Pouliliou, Stamatia, Liousia, Maria V, Giatromanolaki, Alexandra, Koukourakis, Michael I
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Translational Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973160/
https://ncbi.nlm.nih.gov/pubmed/27380135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.202
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