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Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines.

LC3s (MAP1-LC3A, B and C) are structural proteins of autophagosomal membranes, widely used as biomarkers of autophagy. Whether these three LC3 proteins have a similar biological role in autophagy remains obscure. We examine in parallel the subcellular expression patterns of the three LC3 proteins in...

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Detalhes bibliográficos
Main Authors: Michael I Koukourakis, Dimitra Kalamida, Alexandra Giatromanolaki, Christos E Zois, Efthimios Sivridis, Stamatia Pouliliou, Achilleas Mitrakas, Kevin C Gatter, Adrian L Harris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4574774?pdf=render
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