Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines

LC3s (MAP1-LC3A, B and C) are structural proteins of autophagosomal membranes, widely used as biomarkers of autophagy. Whether these three LC3 proteins have a similar biological role in autophagy remains obscure. We examine in parallel the subcellular expression patterns of the three LC3 proteins in...

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Pubblicato in:PLoS One
Autori principali: Koukourakis, Michael I., Kalamida, Dimitra, Giatromanolaki, Alexandra, Zois, Christos E., Sivridis, Efthimios, Pouliliou, Stamatia, Mitrakas, Achilleas, Gatter, Kevin C., Harris, Adrian L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574774/
https://ncbi.nlm.nih.gov/pubmed/26378792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137675
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