Inhibition of IKK-NFκB pathway sensitizes lung cancer cell lines to radiation

OBJECTIVE: : Cancer cell radioresistance is a stumbling block in radiation therapy. The activity in the nuclear factor kappa B (NFκB) pathway correlates with anti-apoptotic mechanisms and increased radioresistance. The IKK complex plays a major role in NFκB activation upon numerous signals. In this...

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Detalhes bibliográficos
Publicado no:Cancer Biol Med
Main Authors: Tsolou, Avgi, Liousia, Maria, Kalamida, Dimitra, Pouliliou, Stamatia, Giatromanolaki, Alexandra, Koukourakis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Chinese Anti-Cancer Association 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570606/
https://ncbi.nlm.nih.gov/pubmed/28884046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2017.0049
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