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Protonation states and catalysis: Molecular dynamics studies of intermediates in tryptophan synthase

The importance of protonation states and proton transfer in pyridoxal 5’‐phosphate (PLP)‐chemistry can hardly be overstated. Although experimental approaches to investigate pKa values can provide general guidance for assigning proton locations, only static pictures of the chemical species are availa...

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Bibliografski detalji
Izdano u:Protein Sci
Glavni autori: Huang, Yu‐ming M., You, Wanli, Caulkins, Bethany G., Dunn, Michael F., Mueller, Leonard J., Chang, Chia‐en A.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815307/
https://ncbi.nlm.nih.gov/pubmed/26013176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2709
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