NMR Crystallography of Enzyme Active Sites: Probing Chemically-Detailed, Three-Dimensional Structure in Tryptophan Synthase

Por Mueller, Leonard J., Dunn, Michael F.
Publicado em 2013

High resolution (13)C-detected solid-state NMR spectroscopy of a deuterated protein

Por Tang, Ming, Comellas, Gemma, Mueller, Leonard J., Rienstra, Chad M.
Publicado em 2010

Resolution and measurement of heteronuclear dipolar couplings of a noncrystalline protein immobilized in a biological supramolecular assembly by proton-detected MAS solid-state NMR...

Por Park, Sang Ho, Yang, Chen, Opella, Stanley J., Mueller, Leonard J.
Publicado em 2013

Investigation of Structural Dynamics of Enzymes and Protonation States of Substrates Using Computational Tools

Por Chang, Chia-En A., Huang, Yu-Ming M., Mueller, Leonard J., You, Wanli
Publicado no Catalysts (2016)

(31)P NMR Investigation of Backbone Dynamics in DNA Binding Sites

Por Tian, Ye, Kayatta, Michael, Shultis, Katharine, Gonzalez, Alejandro, Mueller, Leonard J., Hatcher, Mary E.
Publicado em 2009

Catalytic Roles of βLys87 in Tryptophan Synthase: (15)N Solid State NMR Studies

Por Caulkins, Bethany G., Yang, Chen, Hilario, Eduardo, Fan, Li, Dunn, Michael F., Mueller, Leonard J.
Publicado no Biochim Biophys Acta (2015)

Long-Observation-Window Band-Selective Homonuclear Decoupling: Increased Sensitivity and Resolution in Solid-State NMR Spectroscopy of Proteins

Por Struppe, Jochem O., Yang, Chen, Wang, Yachong, Hernandez, Roy V., Shamansky, Lisa M., Mueller, Leonard J.
Publicado em 2013

Converging Nuclear Magnetic Shielding Calculations with Respect to Basis and System Size in Protein Systems

Por Hartman, Joshua D., Neubauer, Thomas J., Caulkins, Bethany G., Mueller, Leonard J., Beran, Gregory J. O.
Publicado no J Biomol NMR (2015)

Benchmark fragment-based (1)H, (13)C, (15)N and (17)O chemical shift predictions in molecular crystals()

Por Hartman, Joshua D., Kudla, Ryan A., Day, Graeme M., Mueller, Leonard J., Beran, Gregory J. O.
Publicado no Phys Chem Chem Phys (2016)

Protonation states and catalysis: Molecular dynamics studies of intermediates in tryptophan synthase

Por Huang, Yu-ming M., You, Wanli, Caulkins, Bethany G., Dunn, Michael F., Mueller, Leonard J., Chang, Chia-en A.
Publicado no J Mol Recognit (2014)

Protonation states and catalysis: Molecular dynamics studies of intermediates in tryptophan synthase

Por Huang, Yu‐ming M., You, Wanli, Caulkins, Bethany G., Dunn, Michael F., Mueller, Leonard J., Chang, Chia‐en A.
Publicado no Protein Sci (2015)

J – Based 3D Sidechain Correlation in Solid-State Proteins

Por Tian, Ye, Chen, Lingling, Niks, Dimitri, Kaiser, J. Michael, Lai, Jinfeng, Rienstra, Chad M., Dunn, Michael F., Mueller, Leonard J.
Publicado em 2009

Solution-State (17)O Quadrupole Central Transition NMR Spectroscopy in the Active Site of Tryptophan Synthase

Por Young, Robert P., Caulkins, Bethany G., Borchardt, Dan, Bulloch, Daryl N., Larive, Cynthia K., Dunn, Michael F., Mueller, Leonard J.
Publicado no Angew Chem Int Ed Engl (2015)

ALLOSTERY AND SUBSTRATE CHANNELING IN THE TRYPTOPHAN SYNTHASE BIENZYME COMPLEX: EVIDENCE FOR TWO SUBUNIT CONFORMATIONS AND FOUR QUATERNARY STATES

Por Niks, Dimitri, Hilario, Eduardo, Dierkers, Adam, Ngo, Huu, Borchardt, Dan, Neubauer, Thomas J., Fan, Li, Mueller, Leonard J., Dunn, Michael F.
Publicado no Biochemistry (2013)

Visualizing the Tunnel in Tryptophan Synthase with Crystallography: Insights into a Selective Filter for Accommodating Indole and Rejecting Water

Por Hilario, Eduardo, Caulkins, Bethany G., Huang, Yu-Ming M., You, Wanli, Chang, Chia-En A., Mueller, Leonard J., Dunn, Michael F., Fan, Li
Publicado no Biochim Biophys Acta (2015)

NMR Crystallography of a Carbanionic Intermediate in Tryptophan Synthase: Chemical Structure, Tautomerization, and Reaction Specificity

Por Caulkins, Bethany G., Young, Robert P., Kudla, Ryan A., Yang, Chen, Bittbauer, Thomas J., Bastin, Baback, Hilario, Eduardo, Fan, Li, Marsella, Michael J., Dunn, Michael F., Mueller, Leonard J.
Publicado no J Am Chem Soc (2016)

Protonation States of the Tryptophan Synthase Internal Aldimine Active Site from Solid-State NMR Spectroscopy: Direct Observation of the Protonated Schiff Base Linkage to Pyridoxal...

Por Caulkins, Bethany G., Bastin, Baback, Yang, Chen, Neubauer, Thomas J., Young, Robert P., Hilario, Eduardo, Huang, Yu-ming M., Chang, Chia-en A., Fan, Li, Dunn, Michael F., Marsella, Michael J., Mueller, Leonard J.
Publicado em 2014