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Molecular simulations reveal a common binding mode for glycosylase binding of oxidatively damaged DNA lesions
[Image: see text] Cellular DNA is constantly exposed to oxidative stress from both exogenous and endogenous sources, creating lesions that lead to aging related diseases, including cancer. 8-oxo-guanine (8OG) is one of the most common forms of oxidative DNA damage and failure to repair this lesion r...
Uloženo v:
| Vydáno v: | J Am Chem Soc |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814714/ https://ncbi.nlm.nih.gov/pubmed/17988127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja075128w |
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