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Molecular Mechanics Parameters for the FapydG DNA Lesion

FapydG is a common oxidative DNA lesion involving opening of the imidazole ring. It shares the same precursor as 8-oxodG and can be excised by the same enzymes as 8-oxodG. However, the loss of the aromatic imidazole in FapydG results in a reduction of the double bond character between C5 and N7, wit...

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Detalhes bibliográficos
Publicado no:J Comput Chem
Main Authors: Song, Kun, Hornak, Viktor, de los Santos, Carlos, Grollman, Arthur P., Simmerling, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226240/
https://ncbi.nlm.nih.gov/pubmed/17551974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.20625
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