Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake

Cholesterol metabolism is subject to complex transcriptional and nontranscriptional regulation. Herein, the role of ubiquitylation is emerging as an important post-translational modification that regulates cholesterol synthesis and uptake. Similar to other post-translational modifications, ubiquityl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Nelson, Jessica Kristine, Cook, Emma Clare Laura, Loregger, Anke, Hoeksema, Marten Anne, Scheij, Saskia, Kovacevic, Igor, Hordijk, Peter Lodewijk, Ovaa, Huib, Zelcer, Noam
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2016
Pynciau:
Lipids
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813502/
https://ncbi.nlm.nih.gov/pubmed/26719329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.698688
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