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Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons

Spinal muscular atrophy (SMA) is a neurodegenerative disease primarily affecting spinal motor neurons. It is caused by reduced levels of the survival of motor neuron (SMN) protein, which plays an essential role in the biogenesis of spliceosomal small nuclear ribonucleoproteins in all tissues. The et...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Fallini, Claudia, Donlin-Asp, Paul G., Rouanet, Jeremy P., Bassell, Gary J., Rossoll, Wilfried
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812137/
https://ncbi.nlm.nih.gov/pubmed/27030765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2396-15.2016
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