Multiprotein Complexes of the Survival of Motor Neuron Protein SMN with Gemins Traffic to Neuronal Processes and Growth Cones of Motor Neurons

Spinal muscular atrophy (SMA), a progressive neurodegenerative disease affecting motor neurons, is caused by mutations or deletions of the SMN1 gene encoding the survival of motor neuron (SMN) protein. In immortalized non-neuronal cell lines, SMN has been shown to form a ribonucleoprotein (RNP) comp...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhang, Honglai, Xing, Lei, Rossoll, Wilfried, Wichterle, Hynek, Singer, Robert H., Bassell, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956918/
https://ncbi.nlm.nih.gov/pubmed/16914688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3967-05.2006
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